GenInv – Health and Wellness

Researchers from Ohio State University Comprehensive Cancer Center and at the National Cancer Institute has found out a protein that appears to play a essential role in lung cancer in non-smokers. It opens up the possibilities for new lung cancer treatment for this deadly malignancy.

They hope that the new finding (lung cancer treatment) could further improved chemotherapy for lung cancer in both never-smokers and smokers, including those with tumours resistant to targeted drugs such as gefiti

nib and erlotinib.

The findings, published online recently in the Proceedings of the National Academy of Sciences,  They hope that the new finding could further improved chemotherapy for lung cancer in both non smokers and smokers, including those with tumours resistant to targeted drugs such as gefitinib. American and Japanese scientist involved in this new study believe that the miR-21 protein is not only a marker of disease, like PSA levels are in prostate cancer screenings, but an actual

contributor to the cancer process

During examining lung tumors from patient who had never smoked and the research found high levels of a molecule called miR-21. The levels were even higher in tumors that had mutations in a gene called EGFR, a common feature of lung cancer in never-smokers.

 ”Several important lung cancer drugs target EGFR mutations, but these agents are ineffective in about 30 percent of cases in which the mutation is present,” says co-principal investigator Dr. Carlo M.

Croce, professor of molecular virology, immunology and medical genetics at the Ohio State University Comprehensive Cancer Center – James Cancer Hospital and Solove Research Institute. “Our study suggests that developing agents to inhibit miR-21 might improve these anti-EGFR therapies.”

Core and his scientist’s team examined lung cancer sample from 28 cases of lung tumor tissue and all of them are non smoker who had adnocarcinoma. Nearby healthy lung tissue from non smokers for changes in micro RNA, molecules that help cells regulate the kind and amount of proteins they make.

MiR-21 is also elevated in tobacco-related adenocarcinoma, but to a lesser extent. Earlier research also showed that elevated levels of miR-21 and other micro RNAs were markers for poor survival in smoking-related lung cancer. According to researcher Harris.

  The researchers took cells that had a mutated EGFR gene and treated them with an anti-EGFR agent, it related two therapies for specific lung cancers follow the line of scientific though-   gefitinib and erlotinib.  As expected, the drugs were most effective killing the cancer cells. But when they blocked both EGFR and MIR-21, the proportion of cells killed rose still more

 ”It’s a long road from ‘bench to bedside,’” Lichtenfeld said of the findings  ”But clearly this study offers the suggestion that there can be an effective lung cancer treatment for nonsmokers whose adenocarcinoma shows miR-21 elevation

 

 

Source:  Curtis Harris, M.D., U.S. National Cancer Institute, Bethesda, Darrell E. Ward Ohio State University Medical Center, the Intramural Research Program of the National Institutes of Health, National Cancer Institute and Center for Cancer Research

 

Studies have shown that if you are starving yourself, then you aren’t losing weight effectively.  That doesn’t mean that you should just eat anything that you have a craving for, and not eat within moderation.  Yet, it does mean that if you are subscribing to a weight loss strategy that has you missing meals and starving your body, then it will turn out poorly for your overall health.  Breakfast is a meal that many people miss eating, to the detriment of their weight loss goals.  

A mea

l that Americans are having trouble eating is a healthy breakfast.  Studies have shown that a well balanced breakfast is a keystone to a healthy diet and lifestyle.  Many people who are trying to lose weight miss manage breakfast, and that leads to failure in their weight loss ambitions.  Breakfast, as the name of the meal explains, is the breaking of the night’s fast.  Your body has been sleeping, and recharging during the night’s sleep.  When sleeping your body is conserving energy, a

nd partially shutting down.  This partial shutdown slows your body’s metabolism.  The body doesn’t start to metabolize and burn energy, which is how your lose weight, until it takes in some form of nutrients.  That is one of the many reasons why breakfast is essential to losing weight.  Once you eat breakfast, your body will start to burn energy, and prepare for the daily load ahead of it.  

Breakfast foods, especially foods that are prepared in a hurry, can sometimes be huge landmines

to a healthy diet.  Many times breakfast foods can contain a large amount of calories and fats.  While it is usually good to eat foods at breakfast that will give you energy, it is important not to over indulge and eat foods that will sink your calorie count before the day starts.  Fast food breakfasts should be avoided at all cost, also it is important to stay away from foods with high sugars.  Breakfast cereals, breakfast drinks, and breakfast smoothies are all items that can contain a high amount of fats and calories in very small servings.  

Breakfasts that will give energy, and will help in your diet should include items that are low in fats and sugar.  Eggs, oatmeal, fruits, and healthy cereals are all items that can be consumed on a regular basis without killing a diet.  Another item that should be thought about around breakfast time is protein.

Protein supplements are a good way to get your day off on the right foot.  Whey protein supplements are dairy based, so they won’t be hard to digest and will help your body to metabolize at a higher rate.  Whey protein isolates also contain a higher ratio of pure protein than concentrated mixtures or soy based proteins.  Along with a good exercise program your body will use the protein to create lean muscle.  Lean muscle besides adding to the aesthetical beauty of your body, will also burn calories during its creation.  This helps people to lose more weight.  Whey protein should be taken in the morning with breakfast, and right before sleep as both times are ideal for helping your body create lean muscle.  

When trying to lose weight, remember, there isn’t any reason to starve yourself. There are much more effective ways to lose weight.  Through some smart decisions like eating breakfast and adding whey protein to your diet, you will have success.

It is getting hard to breathe deeply. It feels like there are giant hands pressing on your breastbone and your spine. Everything around you is starting to spin. You know that these are all the symptoms of a heart attack. There is only one issue, though. You also know that you are not having one.

A panic attack is a type of anxiety disorder that affects millions of people each year. The attacks can be so debilitating that sufferers often find themselves unable to leave their homes or do simple

everyday tasks. The isolation that is caused by these attacks can lead to depression and inability to function. Thankfully, there are many safe and effective panic attack cures that can help even the most persistent of sufferers.

Instead, you are having a full-blown panic attack. You have already been through this a bunch of times. You and your doctor have discussed what to do to control panic attacks. So, why is this happening again?

Most likely, you have forgotten to do the proper thing

s before arriving at the place you find is causing the attack. There are some very specific ways to prevent panic attacks. This is a much better option than waiting for one to begin and trying to control it.

First and foremost, you must learn to recognize what triggers your panic attacks. These are different for every sufferer, so it is extremely important that you are hones with your doctor and yourself to make sure you are as prepared as possible to fend off another attack.

Next, I sugge

st that you look for alternate ways to handle the business at hand. If you discover that grocery shopping is one major stressor for you, see if there is a different way to go about it. Do you only panic when you are alone? If so, take a companion. Do you find that it is just one specific store that sets you off? Then just find a different store.

If you can find a way to prevent putting yourself in situations that are possible triggers, then do so. A lot of people would say that to really be healed, you should face your demons head on. I heartily disagree. There may be a time when you are ready to go to that place to test your skills at controlling panic attacks, but you should never feel like you must do it.

Since panic attacks are triggered almost exclusively by stress and perceived dangerous situations, throwing yourself into one to prove you are tough is not a good idea. It may take a very long time to get control and forcing the healing process is just going to add to the stress levels. This will, in turn, almost double your chance of having a panic attack immediately.

The absolute best thing to do is to avoid situations that trigger your attacks. However, you can remind yourself to breathe slowly and deeply. Do a lot of self-talk. Tell yourself that you are fine and that there is no real danger. Most importantly, be patient with yourself. There are many people who do not understand panic attacks. You do. Treat yourself kindly.

Particularly, there is no cause of high blood pressure. But, there are some factors which may affect or related to high blood pressure. Likewise, the symptoms of high blood pressure are hard to identify. This is really a silent disease and a silent killer.

These are some of the causes of high blood pressure:

›› Family history- High blood pressure usually runs in the families. If family members have high blood pressure, the rest of the members might have high blood pressure also.

›› Age factor- When a person gets older, the more he is at risk of high blood pressure.

›› Alcohol consumption- Too much alcohol in the body can increase the rate of heart disease over the time.

›› Anxiety- This can lift up the blood pressure.

›› Potassium intake- There should be enough potassium intakes, not lower and not higher too. Because if potassium level is too low, there would be high sodium in the cells.

›› Too muc

h sodium- In can produce fluid preservation and high blood pressure. This is the reason why sodium and potassium work hand in hand. They balance one another.

›› Cigarette smoking- People who smoke usually have heart disease. This is because the chemicals present in the tobacco damages the artery walls.

›› Action- A person who lacks physical activities be likely to increase heart rate. It will push the heart to exert or function more with each contraction.

›

250; Obesity- There would be more pressure on the artery walls if there is a greater body mass. The reason for this is because higher blood is created to provide oxygen and nutrients toward tissues in the body.
Those are some factors that cause high blood pressure. High blood pressure can also be caused by some health conditions fundamental in your history. These medical conditions are kidney disease, thyroid disease, adrenal gland disease, hormonal disorders and use of contraceptives and licorice. If you have these, your high blood pressure is called secondary hypertension. On the other hand, if the cause is unknown, it is called primary hypertension.

How high blood pressure does affect your body?
Usually, high blood pressure include to the workload of your heart and arteries. Because of this your heart should pump harder thus making the arteries to carry blood under a greater pressure. Your heart and arteries will stop working properly if high blood pressure persists for a long time. There would be an increase risk of stroke, kidney failure and heart attack. To those people who are obese, tobacco user, and those who have high blood cholesterol or high blood diabetes have higher risk of stroke.

Blood pressure less than 120/80 mm Hg is the ideal blood pressure but a level that is higher than this increases the risk of cardiovascular diseases.

When your trying to save money on eyeglasses and contacts you want to find a company where you can use coupons and get deals on eye exams, if you have insurance for your eye care it can help but during times like these having healthy eyes is important to maintain. As we age and get older we may find that we need to get glasses finding quality eyewear is probably your foremost priority. Some of the more well known companies that offer deals and eye exam coupons one such store is the Walmart Visio

n Center mostly they are famous and a place for those who are looking to save money they offer discount prices at Wal Mart which has made it a favorite among families, when it comes to the more than vision centers that are open everyday of the week make it easy for those who find themselves traveling they can still use other facilities when shopping. Some of the benefits of Wal Mart Vision Centers is that they have opticians on site as well as a large selection of frames, and if you wear contact

lenses like I do you will be happy to know that they also have a 800 number you can call to order your contacts to have them sent to your home.

If you are looking for frames that offer durablility then you will want to try the Hilco A-2 safety frames for your eyeglasses because they are safer for your job if you use safety glasses, and when it comes to price you are looking at under $30 dollars which I say is a great deal. Empire Vision Centers considered America’s Best is another place that

you can find deals and use eye exam coupons because they cater to the needs of large families that need to save money on their eye care, being a national company they have been around long enough to build trust as well as a loyal customer base. some of there promotional discounts come in the form of coupons, rebates as well as a well known 20/20 program which allow you to save as much as $100 dollars on your contact lenses, keeping your eyes in the best condition possible is necessary especially when you do not want to loose quality at the expense of saving a few bucks. If you wear eyeglasses you will be interested in their 2 pair deal where you get two pairs of eyeglasses for one low price and that includes adults and children, it includes a free eye exam as well as a selection of designer eyewear such as Calvin Klein, Donna Karen and more.

 

Orthopaedic hospital in Bangalore  

Our Associate Orthpaedic Hospitals in Bangalore

Our nation India is best known for heart surgery, hip resurfacing and other areas of latest medicine. The government and private health service centers are committed to the target of making India a leader in the medical tourism industry. The industry’s main focus is least cost treatment. The treatment fees in India start at around one tenth of the price of comparable treatment in the nation like USA

and UK….

Bangalore, one of the fastest growing cosmopolitan cities in Asia also holds the status of being the Silicon Valley of the east. While it has several other reasons to be proud of, perhaps the most important one will be housing some of the most high tech industries in India. Bangalore is also home to some of India’s premier scientific establishments and hospitals.

Blessed with a wonderfully pleasant climate, gardens and parks, natural lakes and several tourist attractions it is d

efinitely a place worth visit. In accordance to its cosmopolitan nature the city of Bangalore is dotted with innumerous pubs, restaurants, shopping malls, nightclubs and other integral facilities that you would find in any major metropolitan.

Bangalore is a hub to few of the finest and medical tourism promoting hospitals of south India. Major medical tourism promoting hospitals in Bangalore are Apollo Hospitals, Bannerghatta Road, Bangalore, Wockhardt Hospitals, , Bannerghatta Road, Bangalore,

Manipal Hospital, Airport Road, Bangalore, Narayana Heart Hospital, Bangalore, Sparsh Orthopedic and Spine Hospital, Bangalore, Sagar Hospital, Bangalore, BGS Global Hospital, Bangalore. These hospitals have been accredited by national and international hospital accreditation bodies and are well equipped to take medical and personal care of International Patients.

 

Other points in favor of India are : -

›› A peaceful democracy for last more than 50 years

›› Independent & mature legal system (although the proceedings are very slow)

›› A wide variety of tourism options.

›› Fixed medical treatment package price that is known in advance…..
 

Our associate hospitals and Joints Replacement Centers are state of the art facilities, equipped with state of art infrastructure and latest technology.

Advanced Diagnostics and Support Infrastructure – 64 slice CT , High end MRI, Neuro-navigation surgical systems, Neuro-physiology and Comprehensive Rehabilitation services Finest quality implants, prosthesis and Consumables of international repute most of them imported from overseas countries are used….

 

Orthopaedic Surgery Procedures at hospitals in Bangalore

Facilities at Orthopaedic Hospitals in Bangalore

›› Operation Theatre equipped with Laminar Air flow

›› State of art Instrumentataion

›› Image Intensifiers….
 

Joint replacements at hospitals in Bangalore

›› Total hip replacement

›› Total knee replacement

›› Total shoulder replacement…
 

Arthroscopic surgery

Key hole surgery for disorders of knee, shoulder, elbow and ankle are offered, in the following manner One day admission….

 

Trauma and Fracture surgery

›› High quality Swiss ‘AO’ systems, help stabilize fractures

›› Image intensifier, confirms perfect fracture fixations….
 

Ilizarov and External Fixation Device

›› Management of open fractures

›› Infected non-union of long bones

›› Limb lengthening

›› Correction of deformities

›› Fusion of joints….
 

Spinal Surgery

›› Disc surgery

›› Micro surgery for disc

›› Fixation Systems for fractures…
 

Arthritis

›› Osteoarthritis

›› Rheumatoid arthritis….
 

Paediatric Orthopaedics

›› Congenital limb & spinal deformities

›› Bone & Joint infections….
 

The orthopaedic department at our partner hospital in India is supported by the most elaborate intensive care services, a modern Accident and Emergency department, and state of the art Physiotherapy and rehabilitation department. They have established trauma protocols for the care of the critically injured patients and principles of Advanced Trauma and Life Support System

A number of vitamins to clear skin are Vitamin A and Vitamin B-complex. These vitamins to clear skin will help keep up healthy skin.

And also Vitamin B5 is another one of the vitamins to clear skin. This vitamin advantage a cream that holds 20 percent pantothenic acid by weight should be applied 4 to 6 times a day.

And other  Vitamins to clear skin can include Vitamin B6 and Vitamin C. Vitamin B6 will help with hormonal balance and Vitamin C get better the immune system also as promotes heali

ng.

Vitamin C – Universally known as ascorbic acid, Vitamin C has been established to help rejuvenate the skin, making it look younger and more lustrous.

Vitamin D – Color and appearance, in common, is the major focus of Vitamin D. Beware when applying any cream or skin care product that contains Vitamin D because extra of it can be reasonably dangerous for your skin.

Vitamin E – If I go to the market to purchase a skin care cream the primary thing I observe is the tag of the product. If it c

ontains natural ingredients then absolutely it stays at the top of my list. Usually a natural skin care cream comes with natural Vitamin E which is recognized as one of the strongest radical destroyers or antioxidants. Thus a excellent skin anti aging cream never comes without Vitamin E in it. You can find Vitamin E during the intakes such as Nuts, Soy beans, Vegetable oil,  etc.

Zinc – Zinc is one more mineral that is excellent in controlling the oil production of the skin. It is extremely he

lpful in treating acne, required for the proper immune system function, good eye sight, smell and taste. It is as well believed to have played a large part in reducing prostate cancer.

EFA Omega 3 – Aside from being a excellent nutrient vital for the proper heart function, Omega 3 is one of the essential fatty acid (EFA) that is needed by body to have healthy skin. It is believe to help moisture, repair and softness of the skin. Good quality sources of Omega 3 are mackerel, baked products, grains, safflower oil and flaxseeds.

These are the very important vitamins you need to take for healthy skin. Vitamins provide defense to your skin from wrinkles and fine lines as well as help to improve the soft, flexible and smooth skin texture. I forever give top priority to food items that are rich with Vitamins and minerals because they do confirm that my skin remains healthy and well protected 24 hours a day. Let your skin have the similar protection and have a healthy shining look.

Facial sweat is normal since it is one way of how our body tries to cool itself down. However, approximately 2-3% of the world’s population is suffering from excessive facial sweating. This is caused by a wide range of reasons such as hereditary genes to a hyperactive sympathetic nervous system. Certain medical illnesses and medications have been known to cause it.

Click Here For Facial Sweat Best Deal Now!

This situation has led many individuals to a lot of embarrassments in front of other

people. Many people who experience excessive facial and body sweating usually have low self-confidence as a result of their dilemma. Some of them have suffered other hygienic problems as a result of their inability to control excessive perspiration.

Many people who have experienced this problem could attest that it is very hard to cure. The medical ointments, creams and tablets that claim to limit facial sweat proved to be temporary answers to their problems. This has led many people frustrated

with their lives aside from wasting a lot of their hard-earned money in purchasing such medications.

This is the very same situation that Mark Montel, author of “Head ‘n Facial Sweating Be Gone” ebook, had gone through before. Faced with these problems, he has look into the problem deeper on his own and as a result, he was able to help 11,000 others to regain their confidence back and live normal lives again.

Unlike other excessive sweating control books, he has written a simple easy-to-

follow guide on how to control excessive facial sweating alone in a very natural, safe and effective way. Facial sweating is a natural body reaction. As such, the most effective way to cure its excesses could also be found in nature.